N-Acetyl L-Tyrosine vs. L-Tyrosine:  N-Acetyl L-Tyrosine is an acetylated derivative of the essential amino acid L-tyrosine. Ordinary L-tyrosine is less stable and insoluble in water, which may result in reduced bioavailability. N-acetyl-L-tyrosine, which is converted in the body to L-tyrosine, is 20 times as soluble in water as L-tyrosine itself. For this reason, it serves as an efficient supplement for raising tyrosine levels in the body, since undissolved substances are not absorbed from the digestive tract. Acetylation enhances the solubility and stability making it a more rapidly absorbed and bioavailable form of the amino acid L-tyrosine which is less prone to urinary excretion.

• Supports Brain Function

• May boost mental energy

• May help with depression

• May enhance athletic performance

L-Tyrosine is an essential amino acid which supports brain function. It can be converted by neurons in the brain into the neurotransmitters dopamine and norepinephrine (noradrenaline), hormones which are depleted by stress, excessive work and certain drugs. By replenishing norepinephrine in the brain, mental energy levels are enhanced and a feeling of contentment often occurs. L-tyrosine boosts certain neurotransmitters in the brain and has been used to support stress reduction and depression. L-Tyrosine is converted in the body into other key biologic compounds, including L-dopa, CoQ10, thyroid hormones and melanin.

Tyrosine can also enhance athletic performance. L-Tyrosine is an important component of protein and helps form the bioactive factors vital to cellular growth and maintenance. Tyrosine supplementation has the potential to increase athletic performance in a few ways. One of the mechanisms possibly contributing to fatigue during exercise is an increase in central serotonin levels and an increase in the ratio of serotonin to dopamine. Tyrosine may help decrease this ratio and compete with tryptophan (the amino acid precursor to serotonin) at the blood-brain barrier. Increased dopaminergic activity may decrease the perception of fatigue. Also, during highly stressful conditions, catecholamine levels can become depleted, and tyrosine may be particularly useful under these conditions.

The B vitamins pyridoxine (B-6) and folic acid can assist in the conversion process.

The amino acid L-tyrosine is a precursor for several substances made in the body:

• neurotransmitters such as dopamine and norepinephrine
• melanins, the pigments largely responsible for skin and hair color
• thyroid hormones, such as thyroxine

  

Suggested Usage: As a dietary supplement take 1 dose (350 mg) 1-2 times daily or as directed by your physician. For maximum benefit, take up to 700 mg per day. Depending on your reaction, effective dosing can be as low as 150 mg per day. Read all label warnings prior to use.

Hypoallergenic: Free of the most common allergens such as yeast, dairy, egg, gluten, corn, soy, rice, barley, lactose, fish and wheat. No added sugars, starch, salt, preservatives, salicylates, or artificial color, flavor or fragrance.

Warning: NOT INTENDED FOR USE BY PERSONS UNDER THE AGE OF 18. KEEP OUT OF THE REACH OF CHILDREN. If you are pregnant or breast feeding, consult your health care professional before using this product. People with known medical conditions and/or taking drugs should consult with a licensed physician and/or pharmacist prior to taking any dietary supplements. Do not take in conjunction with MAO inhibitor drugs. Not for use by persons with a history of malignant melanoma or if bipolar, pregnant, suspect pregnancy, or lactating. Tyrosine should not be taken by those with conditions associated with increased dopamine levels such as mania and schizophrenia. This supplement may increase sensitivity to the effects of CNS stimulants. Caution is advised when taking tyrosine along with stimulants and dosages should be lowered accordingly. Keep out of the reach of children.

L-Tyrosine side effects: L-Tyrosine may help some people in their fight against depression, but dosages above 500 mg, in some people, may cause anxiety, restlessness and rapid heart rate. L Tyrosine can cause over stimulation, restlessness, anxiety, and insomnia. Heart palpitations or arrhythmias are potential side effects that occur from high doses of tyrosine. These can occur in sensitive individuals in as low a dose as 200 to 500 mg. Always start with a low dose, such as 200 mg or less, even if it means opening a tyrosine capsule and taking a portion of it.

We guarantee our supplements to be the freshest and purest available:  This supplement contains absolutely NO additives, sweeteners or other fillers or agents that many manufacturers dilute their products with. NutraBio.com supplements are manufactured under the strictest standards producing the highest quality and purest supplements available anywhere. Our raw ingredients undergo state of the art HPLC analysis to insure zero tolerance for impurities and by-products. When it comes to price and quality you can't beat NutraBio.com. We guarantee it!

Purchase your supplements manufacturer direct at below wholesale price: Buy directly from the manufacturer and save. We cut out the middlemen and pass the savings on to you. With NutraBio.com you can buy your supplements at the same low wholesale price that the chain stores get. We've been around since 1996 and our only business has been the manufacture and supply of the highest quality nutritional supplements. We are a professional nutriceutical, FDA inspected facility which adheres to all FDA, FTC and NNFA labeling and manufacturing guidelines.

Important facts you should know about our supplements:

• HPLC laboratory tested for purity.
• Freshly manufactured - not expired or closeout.
• Spoon mixes with no gritty taste or residue.
• Backed by the NutraBio.com 30-day money back guarantee.
• Free of animal products (except gelatin capsule).

Certificate of Analysis Proves Quality & Freshness:  Always know the expiration date of a supplement before you purchase. If the manufacturer won't give you the expiration date and a Certificate of Analysis than beware. Many online venders sell expired or nearly expired products which they get on closeout from distributors who can no longer sell them to stores. NutraBio.com guarantees that this product is from the freshest and purest raw ingredients available and was packaged within the last two weeks. Click on the red "Purity & Freshness Seal" at the top of the page to view the actual Certificate of analysis.

FREE dosing scoop with your order: Get the exact dosage every time with a free single-dose scoop for pure powder orders. This scoop was designed by our lab to give you exactly one serving each time. No more measuring or guessing.

[1] Tyrosine (and N-Acetyl-L-Tyrosine) [PDF, 232KB] Reform Magazine online John M. Berardi
[2] Hair pigmentation: a research update. J Investig Dermatol Symp Proc. 2005 Dec;10(3):275-9 Tobin DJ, Hordinsky M, Bernard BA
[3] The actions of melanin and melanocyte stimulating hormone (MSH) Neuroendocrinology Letters 1999; 20:265–282 Natalie Rasmussen, Francine Nelson, Piyarat Govitrapong, Manuchair Ebadi
[4] Melanin [monograph] Wikipedia online encyclopedia
[5] Tyrosine [monograph] Wikipedia online encyclopedia
[6] Dopaminergic deficit and mood disorders. Int Clin Psychopharmacol. 2002 Dec;17 Suppl 4:S1-7; discussion S7 Pania L, Gessab GL
[7] Chronic mild stress (CMS) revisited: consistency and behavioural-neurobiological concordance in the effects of CMS. Neuropsychobiology. 2005;52(2):90-110. Epub 2005 Jul 19 Willner P
[8] [L-tyrosine cures, immediate and long term, dopamine-dependent depressions. Clinical and polygraphic studies][Article in French] C R Acad Sci III. 1988;306(3):93-8 Mouret J, Lemoine P, Minuit MP, Robelin N
[9] Tyrosine for the treatment of depression. Nutr Health. 1984;3(3):163-73 Gelenberg AJ, Gibson CJ
[10] Tyrosine improves cognitive performance and reduces blood pressure in cadets after one week of a combat training course. Brain Res Bull. 1999 Jan 15;48(2):203-9 Deijen JB, Wientjes CJ, Vullinghs HF, Cloin PA, Langefeld JJ.
[11] Cats require more dietary phenylalanine or tyrosine for melanin deposition in hair than for maximal growth. J Nutr. 2002 Jul;132(7):2037-42 Anderson PJ, Rogers QR, Morris JG
[12] Vitiligo therapy with oral and topical phenylalanine with UVA exposure. Int J Dermatol. 1989 Oct;28(8):545-7 Antoniou C, Schulpis H, Michas T, Katsambas A, Frajis N, Tsagaraki S, Stratigos J
[13] Evidence for antioxidant nutrients-induced pigmentation in skin: results of a clinical trial. Biochem Mol Biol Int. 1997 Aug;42(5):1023-33 Postaire E, Jungmann H, Bejot M, Heinrich U, Tronnier H
[14] Stimulation of mouse melanocyte proliferation by Piper nigrum fruit extract and its main alkaloid, piperine. Planta Med 1999 Oct;65(7):600-3 Lin Z, Hoult JR, Bennett DC, Raman A
[15] Chronic dietary tyrosine supplements do not affect mild essential hypertension. Hypertension. 1985 Jul-Aug;7(4):593-6 Sole MJ, Benedict CR, Myers MG, Leenen FH, Anderson GH
[16] [L-tyrosine: a long term treatment of Parkinson's disease][Article in French] C R Acad Sci III. 1989;309(2):43-7 Lemoine P, Robelin N, Sebert P, Mouret J

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