Knowledge Bomb - OKG

L-ORNITHINE ALPHA-KETOGLUTARATE 2:1 REACTED (OKG)
  • OKG is a combination of two molecules of the nonessential amino acid, ornithine, bound to alpha-ketoglutarate. OKG has been shown to stimulate an increase in arginine, plasma glutamate, and intramuscular glutamine, as well as stimulate an increase in insulin secretion, nitric oxide synthesis, HGH, and IGF1. The increases in these substances due to OKG promote anabolic and anti-catabolic responses in the body which may play a role in boosting recovery.
  • OKG may also improve exercise performance by reducing ammonia concentrations in the blood thus lessening fatigue of working muscles.
  • OKG plays a supporting role in muscle protein synthesis
  • Suqino et al. (2008) found those supplementing with L-ornithine for 6 days were able to reduce perceptions of fatigue by 52% compared to placebo. The author also observed that ammonia accrual during exercise was reduced compared to placebo.
  • NutraBio's OKG is fully reacted, which means it is positively bonded. It is the exact same form that the positive research studies were based on.